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- Original Article
- Outcome of inflammatory response after normothermia during cardiopulmonary bypass surgery in infants with isolated ventricular septal defect
- Dong Sub Kim, Sang In Lee, Sang Bum Lee, Myung Chul Hyun, Joon Yong Cho, Young Ok Lee
- Clin Exp Pediatr. 2014;57(5):222-225. Published online May 31, 2014
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Purpose A recent study analyzing several cytokines reported that long cardiopulmonary bypass (CPB) time and long aortic cross clamp (ACC) time were accompanied by enhanced postoperative inflammation, which contrasted with the modest influence of the degree of hypothermia. In this present study, we aimed to examine the effect of CPB temperature on the clinical outcome in infants undergoing repair of isolated...
- Predictors of nonresponse to intravenous immunoglobulin therapy in Kawasaki disease
- Hyo Min Park, Dong Won Lee, Myung Chul Hyun, Sang Bum Lee
- Clin Exp Pediatr. 2013;56(2):75-79. Published online February 25, 2013
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Purpose It has been reported that 10% to 20% of children with Kawasaki disease (KD) will not respond to intravenous immunoglobulin (IVIG) treatment. In this study, we aimed to identify useful predictors of therapeutic failure in children with KD.
Methods We examined 309 children diagnosed with KD at the Kyungpook National University Hospital and the Inje University Busan Paik Hospital between January 2005...
- Clinical features and surgical outcomes of complete transposition of the great arteries
- Suk Jin Hong, Hee Joung Choi, Yeo Hyang Kim, Myung Chul Hyun, Sang Bum Lee, Joon Yong Cho
- Clin Exp Pediatr. 2012;55(10):377-382. Published online October 29, 2012
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Purpose This single-center study aimed to assess the clinical features and surgical approaches and outcomes of complete transposition of the great arteries (TGA).
Methods TGA patients who had undergone surgical correction at the Kyungpook National University Hospital from January 2000 to December 2010, were retrospectively evaluated for patient characteristics, clinical manifestation, preoperative management, intraoperative findings, postoperative progress, and follow-up status.
Results Twenty-eight patients (17 boys...
- Wolff-Parkinson-White syndrome in young people, from childhood to young adulthood: relationships between age and clinical and electrophysiological findings
- Hae Jung Jung, Hwang Young Ju, Myung Chul Hyun, Sang Bum Lee, Yeo Hyang Kim
- Clin Exp Pediatr. 2011;54(12):507-511. Published online December 31, 2011
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Purpose The aim of the present study was to evaluate the characteristics of electrophysiologic studies (EPS) and radiofrequency ablation (RFA) performed in subjects aged less than 30 years with Wolff-Parkinson-White (WPW) syndrome, particularly pediatric patients under 18 years of age, based on our experience.
Methods Two hundred and one consecutive patients with WPW syndrome were recruited and divided to 3 groups according to...
- Early postoperative arrhythmias after open heart surgery of pediatric congenital heart diseas
- Hee Joung Choi, Yeo Hyang Kim, Joon Yong Cho, Myung Chul Hyun, Sang Bum Lee, Kyu Tae Kim
- Clin Exp Pediatr. 2010;53(4):532-537. Published online April 15, 2010
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Purpose : Early postoperative arrhythmias are a major cause of mortality and morbidity after open heart surgery in the pediatric population. We evaluated the incidence and risk factors of early postoperative arrhythmias after surgery of congenital heart disease. Methods : From January 2002 to December 2008, we retrospectively reviewed the medical records of the 561 patients who underwent cardiac surgery in Kyungpook National University... -
- NT-proBNP as a useful tool in diagnosing incomplete Kawasaki disease
- Dong Won Lee, Yeo Hyang Kim, Myung Chul Hyun, Tae Chan Kwon, Sang Bum Lee
- Clin Exp Pediatr. 2010;53(4):519-524. Published online April 15, 2010
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Purpose : To determine the efficacy of the N-terminal fragment of B-type natriuretic peptide (NT-proBNP) as a useful diagnostic method in children with incomplete Kawasaki disease (KD). Methods : Ninety-six patients who were diagnosed as having KD between January 2008 and June 2009 were enrolled in the study. American Heart Association recommendations for diagnosis were used, and patients were divided into... -
- The changes in signal-averaged electrocardiogram after surgical correction of congenital heart disease
- Yeo Hyang Kim, Hee Jung Choi, Gun Jik Kim, Joon Yong Cho, Myung Chul Hyun, Sang Bum Lee
- Clin Exp Pediatr. 2009;52(12):1364-1369. Published online December 15, 2009
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Purpose : To analyze abnormal ventricular activation in childhood congenital heart disease induced by postoperative changes in ventricular volume and pressure and ventricular scar formation using signal-averaged electrocardiography (SAECG). Methods : Fifty-two patients who had undergone open heart surgery (OHS) were enrolled. Patients were divided into the following 3 groups: right ventricular volume overload (atrial septal defect, group1), left ventricular... -
- Clinical features and results of recent total anomalous pulmonary venous connection : Experience in a university hospital (Clinical study of total anomalous pulmonary venous connection)
- Mi Ae Chu, Byung Ho Choi, Hee Joung Choi, Yeo Hyang Kim, Joon Yong Cho, Myung Chul Hyun, Sang Bum Lee
- Clin Exp Pediatr. 2009;52(2):194-198. Published online February 15, 2009
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Purpose : Active perioperative intervention and improvement on surgical technique has decreased the mortality rate of total anomalous pulmonary venous connection (TAPVC); however, when complicated with pulmonary venous obstruction, operative mortality is still high. The purpose of this study was to investigate the clinical course of TAPVC. Methods : Twenty-seven patients who were diagnosed with TAPVC (without other complex heart... -
- Epidemiologic study of Kawasaki disease in 6 months old and younger infants
- Yong Won Park, Ji Whan Han, In Sook Park, Chang Hwi Kim, Sung Ho Cha, Jae Sook Ma, Joon Sung Lee, Tae Chan Kwon, Sang Bum Lee, Chul Ho Kim, Heung Jae Lee, Yong Soo Yun
- Clin Exp Pediatr. 2008;51(12):1320-1323. Published online December 15, 2008
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Purpose : The aim of this study was to investigate the epidemiologic status of Kawasaki disease (KD) in infants ≤6 months of age. Methods : For the epidemiologic study of KD in Korea, data from 22,674 KD patients were collected from 1997 to 2005 on a 3-year basis by a retrospective survey. From this survey, data of 1,739 KD patients ≤6... -
- Clinical features and results of recent neonatal cardiac surgery - A review of 82 cases in one hospital
- Ki Won Oh, Jung Ok Kim, Joon Yong Cho, Myung Chul Hyun, Sang Bum Lee
- Clin Exp Pediatr. 2007;50(7):665-671. Published online July 15, 2007
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Purpose : The purpose of this study was to investigate the clinical features and outcome in newborns undergoing cardiac surgery. Methods : Eighty two neonates underwent heart surgery for congenital heart defect at Kyungpook National University Hospital between March 2000 and February 2006. Patient characteristics (sex, age, diagnosis), pre-operative conditions, operation type, postoperative complications and mortality were reviewed retrospectively. Results : In... -
- Clinical features and surgical results of ruptured sinus of valsalva aneurysm
- Tae Ho Lee, Dong Won Lee, Joon Yong Cho, Myung Chul Hyun, Sang Bum Lee
- Clin Exp Pediatr. 2006;49(3):287-291. Published online March 15, 2006
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Purpose : Aneurysms of sinus valsalva are rare anormalies thought to be primarily congenital in origin, progressing into death by acute heart failure in cases of rupture. Surgical correction is the only method of treatment. With these clinical implications, we reviewed the clinical characteristics and surgical results of patients with ruptured sinus of valsalva aneurysm. Methods : Between January 1991... -
- Clinical and Epidemiologic Study of Kawasaki Disease in Children 8 Years of Age and Older
- Yong Won Park, Ji Whan Han, In Sook Park, Chang Hwi Kim, Sung Ho Cha, Jae Sook Ma, Tae Chan Kwon, Sang Bum Lee, Chul Ho Kim, Heung Jae Lee, Yong Soo Yun
- Clin Exp Pediatr. 2005;48(10):1139-1142. Published online October 15, 2005
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Purpose : The aim of this study was to investigate the epidemiologic and clinical profiles of Kawasaki disease(KD) in children 8 years of age and older. Methods : For the epidemiologic study of KD in Korea, data of total 15,692 KD patients were collected from 1994 to 2002 on a 3 year basis, by the retrospective survey. Among them, data of... -
- Quantitative Assessment of Myocardial Tissue Velocity in Normal Children with Doppler Tissue Imaging : Reference Values, Growth and Heart Rate Related Change
- Se Young Kim, Myung Chul Hyun, Sang Bum Lee
- Clin Exp Pediatr. 2005;48(8):846-856. Published online August 15, 2005
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Purpose : To measure the peak myocardial tissue velocities and patterns of longitudinal motion of atrioventricular(AV) annuli and assess body weight and heart rates-related changes in normal children. Methods : Using pulsed wave Tissue Doppler Imaging(TDI), we measurpeak systolic, early and late diastolic myocardial velocities in 72 normal children at six different sites in apical-4 chamber (A4C) view and at... -
- Usefulness of Intraoperative Transesophageal Echocardiography
- Dong Won Lee, Byung Mok Kim, Sei Young Kim, Yeo Hyang Kim, Myung Chul Hyun, Sang Bum Lee
- Clin Exp Pediatr. 2004;47(12):1281-1286. Published online December 15, 2004
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Purpose : This study was undertaken to learn the usefulness, cost-effectiveness and safety of intraoperative transesophageal echocardiography(ITEE) during open heart surgery for congenital heart diseases. Methods : The usefulness and safety of ITEE were assessed in 254 patients who underwent open heart surgery for congenital heart diseases from January 1, 2001 to June 30, 2003, with retrospective chart reviews and a... -
- Abnormality of Regional Wall Motion of the Left Ventricle in Children with Ventricular Diastolic Overload
- Yeo Hyang Kim, Sang Bum Lee
- Clin Exp Pediatr. 2004;47(1):49-54. Published online January 15, 2004
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Purpose : To assess the regional wall motion of the left ventricle in patients with diastolic overloaded lesions of congenital heart diseases with centerline analysis and radial method. Methods : This study included 96 children with congenital heart diseases admitted to Kyungpook National University Hospital from January 1998 to December 2002 who received left ventriculograms. The evaluation of the regional wall... -
- Echocardiographic Parameters of Pulmonary Atresia with Intact Ventricular Septum(PA/IVS)
- Young Seok Lee, Yeo Hyang Kim, Myung Chul Hyum, Sang Bum Lee
- Clin Exp Pediatr. 2003;46(5):484-489. Published online May 15, 2003
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Purpose : To understand morphologic and hemodynamic variations in patients with pulmonary atresia with intact ventricular septum(PA/IVS), and to decide the best treatment modalities, we measured right ventricular volume, inflow, and outflow valvular annulus size in these patients and compared them with those of normal newborns. Methods : Eight patients with PA/IVS diagnosed by echocardiography from January to December 2001... -
- Hypoxia Induced Expression of Vascular Endothelial Growth Factor in Rat Pulmonary Artery Smooth Muscle Cells
- Un Seok Nho, Yeo Hyang Kim, Myung Chul Hyun, Sang Bum Lee
- Clin Exp Pediatr. 2003;46(2):167-172. Published online February 15, 2003
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5% CO2-95% air atmosphere. The smooth muscle cells were confirmed by immunostaining with smooth muscle myosin and α-smooth muscle actin antibodies. The VEGF gene expression in the hypoxic group was compared with the one in control the group as well as the one in the starved group by RT-PCR and Northern blot hybridization. Results : There was no statistically significant difference... -
- Serial Changes of Cardiac Troponin I After Pediatric Open Heart Surgery
- Yeo Hyang Kim, Myung Chul Hyun, Sang Bum Lee
- Clin Exp Pediatr. 2002;45(2):208-213. Published online February 15, 2002
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Purpose : The major cause of cardiac dysfunction, after open heart surgery for congenital heart disease, is perioperative myocardial injury. Cardiac troponin I is found only within the myocardial cell, so it can be used as a biochemical marker of the myocardial injury. We performed this study to evaluate the worth of cardiac troponin I as a biochemical marker reflecting... -
- The Changes of Production of RANTES and Gro-α in Kawasaki Disease
- Young Hwan Lee, Hyun Kyung Lee, Bo Hyeong Lee, Sun Yoon Jung, Hee Sun Kim, Sang Bum Lee
- Clin Exp Pediatr. 2001;44(9):1002-1011. Published online September 15, 2001
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Purpose : Kawasaki disease is probably driven by abnormalities of the immune system after infectious insult. In this report, a clinical review with laboratory parameters and the changes of the plasma levels of chemokines(RANTES and Gro-α) was undertaken according to the clinical stage of Kawasaki disease. Methods : This investigation included 74 samples from 21 patients(10 boys, 11 girls; mean age, 27.8 months) with Kawasaki... -
- Transcatheter Closure of the Patent Ductus Arteriosus
- Young A Lee, Myung Chul Hyun, Sang Bum Lee
- Clin Exp Pediatr. 2000;43(9):1200-1206. Published online September 15, 2000
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Purpose : Transcatheter closure of the patent ductus arteriosus(PDA) is a well-established, effective therapeutic modality, and many kinds of devices have been used to perform this closure. The aim of this study is to compare the effects of different kinds of devices. Methods : We reviewed retrospectively the charts of 43 patients who were admitted to Kyungpook University Hospital between June... -
- Morphometric Analysis of the Infundibulum in Tetralogy of Fallot
- Su Hee Kwak, Myung Chul Hyun, Sang Bum Lee
- Clin Exp Pediatr. 2000;43(9):1187-1191. Published online September 15, 2000
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Purpose : The morphogenic mechanism of tetralogy of Fallot is known to be an antero-superior deviation and hypertrophy of the subpulmonary infundibulum. We performed this study to measure the subpulmonary infundibulum in patients with tetralogy of Fallot and compare those with normal control. Methods : Echocardiographic data and medical reports of 12 patients, with classical tetralogy of Fallot who were diagnosed... -
- Short-term Result of Radiofrequency Catheter Ablation in Pediatric Patients with Paroxysmal Tachycardia
- Hee Suk Jang, Hee Jung Cho, Myung Chul Hyun, Sang Bum Lee, Young Keun Cho, Chang Ho Han
- Clin Exp Pediatr. 2000;43(2):203-209. Published online February 15, 2000
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Purpose : To find out the efficacy, safety and early complication of radiofrequency catheter ablation(RFCA) in pediatric patients with paroxysmal tachycardia, we compared short-term results of RFCA in pediatric patients to adult patients. Methods : We studied 25 patients(11 pediatric patients, 14 adult patients), who underwent RFCA due to paroxysmal supraventricular tachycardia(PSVT) or idiopathic ventricular tachycardia(VT) from November 1997 to August... -
- Depolarization, Repolarization Inhomogeneity and Late Potential after Surgical Repair of Tetralogy of Fallot
- Soo Young Kim, Myung Chul Hyun, Sang Bum Lee, Seung Tae Kim, Jong Soo Lee
- Clin Exp Pediatr. 1999;42(8):1071-1077. Published online August 15, 1999
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Purpose : After repair of tetralogy of Fallot(TOF), ventricular arrhythmia and sudden death remain as serious late complications which are due to right ventricular systolic and diastolic overloading, exposure to hypoxia and surgical scar. Among the various methods for predicting the risk of such complications, we evaluated signal average ECG(SAECG), QRS duration, QT and JT dispersion, cardiothoracic(CT) ratio, age at... -
- Assessment of Regional Wall Motion of the Left Ventricle in Children with Congenital Heart Disease
- Chang Hee Han, Jun Ho Huh, Un Seok Nho, Byung Ho Choi, Myung Chul Hyun, Sang Bum Lee
- Clin Exp Pediatr. 1999;42(6):807-816. Published online June 15, 1999
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Purpose : To assess wall motion of the left ventricle in the various forms of congenital heart disease and to select appropriate methods by which to gauge left ventricular wall motion. Methods : We evaluated left ventricular function, including volume, global ejection fraction, and regional wall motion(Centerline method, Local Ejection Fraction, Curved Perimeter method and Radial method). The evaluation was done... -
- Clinical Observations of Coarctation of the Aorta
- Hui Jung Cho, Chang Ho Ha, Dong Seok Lee, Myung Chul Hyun, Sang Bum Lee
- Clin Exp Pediatr. 1999;42(4):519-525. Published online April 15, 1999
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Purpose : Due to controveries surrounding in the incidence of coarctation of aorta which reports previously stated rare among Orientals, we evaluated clinical characteristics, natural courses of coarctation of aorta and effects of different surgical modalities. Methods : Medical records of 51 patients with coarctation of aorta, diagnosed by 2-dimensional echocardiography in Kyungpook University Hospital Pediatric Cardiac Laboratory from June 1985... -
- Fixed Subaortic Stenosis in Children
- Eun Jin Choi, Byung Ho Choi, Myung Chul Hyun, Sang Bum Lee
- Clin Exp Pediatr. 1997;40(4):505-511. Published online April 15, 1997
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Purpose : This study attempted to describe the Doppler and two-dimensional echocardiographic features of fixed subaortic stenosis, the de novo occurrence and progression of this lesion and to review its etiology, treatment and course. Methods : We studied 17 patients of fixed subaortic stenosis who, between Jan. 1993 and Jan. 1996, ware diagnosed by echocardiographic examination at Kyungpook National University Hospital.... -
- Clinical Lecture
- Clinical Presentation of Heart Diseasein Infants and Children
- Sang Bum Lee
- Clin Exp Pediatr. 1997;40(3):301-306. Published online March 15, 1997
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- Original Article
- Myocardial Functions Estimated by Pulsed Doppler Echocardiography in Patientswith Chronic Renal Failure
- Hyun June Huh, Byung Ho Choi, Myung Chul Hyun, Sang Bum Lee
- Clin Exp Pediatr. 1996;39(12):1712-1728. Published online December 15, 1996
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Purpose : The objectives of this study were to estimate myocardial functions in patients with chronic renal failure by pulsed Doppler echocardiography, and investigate correlation between Doppler and disease parameters. Methods : We studied 13 patients with chronic renal failure whose creatinine clearance rate less than 25ml/min. Using pulsed Doppler echocardiography with curve following method, we measured peak velocity, mean velocity, velocity-time integral and peak... -
- Clinical Course of the Ostium Secundum Atrial Septal Defect(ASD) and Its Rate of Spontaneous Closure
- Dae Yong Kim, Myung Chul Hyun, Sang Bum Lee
- Clin Exp Pediatr. 1996;39(11):1538-1543. Published online November 15, 1996
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Purpose : To know the natural course of the ostium secundum ASD including its rate of spontaneous closure. Methods : We studied 259 cases who were diagnosed as ostium secundum ASD by 2D-echocardiography at Department of Pediatrics, Kyungpook National University Hospital between Jan. 1985 and Dec. 1994. According to the age at diagnosis, we divided them into two groups, group I (those diagnosed before 1... -
- Clinical Course of Atrioventricular Septal Defect(AVSD) in Down and non Down syndrome
- Un Seok Nho, Myung Chul Hyun, Sang Bum Lee
- Clin Exp Pediatr. 1996;39(9):1288-1294. Published online September 15, 1996
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Purpose : It is well known that 1/3 - 1/2 of Atrioventricular septal defect(AVSD) patients also have Down syndrome which may influence the clinical course of AVSD. To know the anatomic type of AVSD and the effect of Down syndrome on the clinical course of AVSD, we studied 37 cases( Down group: 14 cases, non Down group: 23 cases) who were diagnosed and... -
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Impact Factor4.2
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6.52022CiteScore92nd percentilePowered by
